I voted 'YES' with the qualifier that he has to serve over 65% on the first delivery and be punishing on both. I think that is his most effective weapon against both Nole & Rafa. If he can keep them off balance and not allow them to make any inroads on his service, he has a fair chance to break either of them (especially Nadal) once per set over the course of a match.
I won't be wagering any cold cash on that happening though, as most players seem quite content to practice bashing groundies instead of focusing on the 2 most important shots in the game-- The Serve & The Return.