Interesting footnote to Serena's long run of domination: there was a lost generation.
Yes, and her own generation has also been hard hit. Hingis left far to soon - after all these years, she is still the one from her generation with most weeks as #1. Both Belgians disappeared too soon, as did Myskina.
Btw, I wouldn't speak about "long run of domination". She dominated 2002 - early 2003. Since then she's more often than not been one of the top figures, but never dominated. Even when she topped the rankings in 2009 she was never very far ahead of #2. And as late as 2008, before the first retirement, her younger competitor Justine Henin had better career stats than her.